nordicICE

Advanced MRI Perfusion Software

nordicICE couples a perfusion package and a permeability analysis package. With these modules a large range of physiologically relevant parameters related to tissue perfusion and capillary permeability can be addressed both qualitatively and semi-quantitatively using state-of-the-art methods.

With nordicICE the user can generate high-quality perfusion maps for DSC, DCE and ASL in seconds. The advanced Batch processing module can be configured to process all your perfusion data with a few clicks.

The combination of advanced features, a user-friendly interface, myriads of options and possibilities, robust algorithms and fast processing times makes nordicICE the ideal tool for clinical research, particularly for Perfusion.

nordicICE implements advanced analysis methods for:

  • Dynamic susceptibility contrast perfusion (DSC)
  • Dynamic contrast enhanced perfusion (DCE)

  • Arterial Spin Labeling flow perfusion (ASL)

    Modules & Functionality:

  • Perfusion DSC and permeability DCE
  • Arterial Spin Labeling (ASL)
  • Relaxometry (T1 & T2 mapping)
  • Diffusion Weighted Imaging (DWI)
  • DTI
  • BOLD fMRI
  • Batch processing
  • DICOM database

  • Wide range of general image analysis tools

    Batch functionality for processing of many datasets:

  • Image conversion, downsampling, resampling
  • Pre-processing
  • Motion correction
  • Normalize and Mask
  • ROI analysis
  • Image pixel extraction with easy export of data to Excel for further analysis
  • Perfusion analysis
  • DCE analysis
  • T1 relaxation analysis



nordicICE is a research only application - no clinical approvals.

DSC Perfusion

Fast generation of perfusion maps: Blood volume (CBV), Blood flow (CBF), Mean Transit Time (MTT), Time to Peak (TTP) or Delay (SVD), Leakage (Ktrans), Brain Mask, Vessel Mask.
State-of-the-art deconvolution techniques, choice of manual or fully automatic selection of arterial input function, automated calculation of leakage map when the BBB is disrupted (leakage map - Ktrans), vessel removal algorithm for increased accuracy in evaluation of maps. Create normalized CBV maps. Combine perfusion and diffusion imaging for stroke evaluation.

DCE Perfusion

Quantitative maps: intra-extravascular leakage, extra-intravascular reflux, extravascular-extracellular space, plasma volume fraction.
Qualitative maps: area under curve, time to peak, peak enhancement, wash-in/wash-out rates

Related news articles:

14 March 2016 nordicICE 4.0.4
9 February 2016 nordicICE 4.0.3
17 September 2015 nordicICE 4.0 Seminar
15 September 2015 nordicICE 4.0